- Sam BrownFormed / started: 7 October 1964Note: UK singer/songwriter
- Sandy DennyFormed / started: 6 January 1947Split up / ended: 21 April 1978
- Sarah Jezebel DevaBorn in: LondonDecade started: 1980s
- SashaFormed / started: 4 September 1969Note: UK DJ/producer Alexander Paul Coe
- ScarlxrdFormed / started: 19 June 1994Note: rapper
- Scott WalkerFormed / started: 9 January 1943Note: singer‐songwriter, musician and producer
- Screaming Lord SutchFormed / started: 10 November 1940Split up / ended: 16 June 1999
- SealFormed / started: 19 February 1963Note: English‐born singer and songwriter
- Shane MacGowanFormed / started: 25 December 1957Split up / ended: 30 November 2023
- Sid ViciousFormed / started: 10 May 1957Split up / ended: 2 February 1979
- Simon DawsonBorn in: SuffolkGenres: rock music
- Simon LaffyBorn in: FinchleyDecade started: 1950s
- Simon WrightFormed / started: 19 June 1963Note: rock and metal drummer
- Simon WrightBorn in: OldhamDecade started: 1970s
- Snowy WhiteFormed / started: 3 March 1948Note: guitarist
- Sonia JonesDecade started: 1970sGenres: rock music
- Soo CatwomanFormed / started: 24 October 1954Split up / ended: 30 September 2025
- Stephen LargeDecade started: 2000sGenres: rock music
- Steve ByrdFormed / started: 1955Split up / ended: 2 October 2016
- Steve ClarkBorn in: SheffieldDecade started: 1970s
- Steve DawsonBorn in: SheffieldDecade started: 1970s
- Steve FirthBorn in: HalifaxDecade started: 1960s
- Steve GouldingBorn in: South LondonDecade started: 1950s
- Steve GrantleyDecade started: 1960sGenres: rock music
- Steve GrimmettFormed / started: 19 August 1959Split up / ended: 15 August 2022
- Steve GrimmettBorn in: SwindonDecade started: 1970s
- Steve HarleyFormed / started: 27 February 1951Split up / ended: 17 March 2024
- Steve HarrisFormed / started: 12 March 1956Note: Iron Maiden bassist
- Steve HarrisBorn in: LondonDecade started: 1970s
- Steve JonesBorn in: Shepherd's BushDecade started: 1970s
- Steve LyonBorn in: TwickenhamDecade started: 1960s
- Steve MarriottFormed / started: 30 January 1945Split up / ended: 20 April 1991
- Steve RamseyDecade started: 1980sGenres: heavy metal music
- Steve WallerBorn in: Herne HillDecade started: 1970s
- Steve WhiteBorn in: BermondseyDecade started: 1980s
- Steve WilliamsBorn in: WalesDecade started: 1970s
- Steven A. WilliamsBorn in: CoventryDecade started: 1980s
- Steven WilsonFormed / started: 3 November 1967Note: founder of Porcupine Tree
- Stevie BillBorn in: AmsterdamDecade started: 2020s
- Stevie MannBorn in: BelfastDecade started: 1970s
- Stuart AnstisFormed / started: 2 May 1974Split up / ended: 21 August 2022
- Stuart FletcherBorn in: YorkDecade started: 1990s
- Stuart SmithDecade started: 1950sGenres: rock music
- Stuart SutcliffeFormed / started: 23 June 1940Split up / ended: 10 April 1962
- Stuart WoodBorn in: EdinburghDecade started: 1970s
- Stuart “Woolly” WolstenholmeFormed / started: 15 April 1947Split up / ended: 13 December 2010
- Syd BarrettFormed / started: 6 January 1946Split up / ended: 7 July 2006